RaySearch Laboratories announced the treatment of the first patient using a new adaptive replanning module within the latest version of RayStation at the Royal Marsden NHS Foundation Trust in the UK.
The development took place in March 2025, employing Accuray’s Radixact treatment machine in conjunction with Royal Marsden’s existing oncology information system.
RayStation is a treatment planning system that includes features such as adaptive therapy and multi-criteria optimisation. It supports a range of treatment machines and integrates seamlessly with RayCare, enhancing the efficiency of cancer treatment planning.
According to RaySearch, the procedure at Royal Marsden showed the effectiveness of RayStation’s new module, offering considerable time savings for patients and the hospital. Despite this progress, there is potential for further optimisation in system communication, said RaySearch.
Teams from RaySearch and The Royal Marsden are working together to refine integration and improve system efficiency.
RaySearch founder and CEO Johan Löf said: “Online adaptive has been a key focus for RaySearch for many years and I am happy that The Royal Marsden has treated its first patient using this groundbreaking RayStation technology.
“RayStation has very advanced tools available for taking online adaptive into clinical practice, and we look forward to collaborating with the team at The Royal Marsden to further improve efficiency in this field, and thereby advance cancer treatment.”
The next step involves integrating RaySearch’s oncology information system, RayCare, which is anticipated to further decrease treatment times. RayCare addresses logistical challenges in oncology clinics by providing workflow automation and adaptive radiation therapy features.
For users of RaySearch software, an online adaptive workflow can be implemented regardless of the treatment machine type, paving the way for broader adoption of online adaptive radiotherapy.
The first patient treated under this new workflow received radical treatment for endometrial cancer on a Radixact linear accelerator.
Royal Marsden consultant clinical oncologist Susan Lalondrelle said: “We are extremely proud to be the first cancer centre in the world to treat a patient using RaySearch’s advanced online adaptive radiotherapy technology, and we are hugely grateful to The Royal Marsden Cancer Charity for funding this vital equipment.
“Being able to tailor each treatment session to the patient’s current anatomy, while the patient is on the treatment bed, is a major step forward in delivering more personalised cancer care.”
