Contract manufacturing 1 Top
3D-printed custom implants used for robotic surgery to for bone cancer patients are a new medtech frontier. A combination of 3D printing, robotic surgery and advanced manufacturing are being used by RMIT University in Australia in conjunction with medtech giant Stryker to create tailored implants for patients with bone cancer. While patients are having their cancer removed in the operating theatre, in the next room, a custom implant will be printed to precisely fill the space left after removal of the diseased bone. We speak to Stryker’s director, research and development for Asia-Pacific, Rob Wood, who explains how 3D printing is opening new doors for manufacturing in healthcare.
Contract manufacturing 2 Top
Uncovering strategies to maintain project timelines, reduce unexpected added costs and maintain trial budgets are big problem. We speak to Torsten Kayser, senior clinical research fellow, Boston Scientific, about how best to present strategies for CMOs contract management – how can you incentivise your vendors to work to your timelines and the necessary things to do when investigating strategies to persuade your notified bodies to validate your post market surveillance data.
Contract manufacturing 3 Top
More traditional contract manufacturers are embracing diversification to keep up with the changing market and keep themselves competitive. Medical Device Developments explores how more and more CMOs are offering more than just end-to-end services, and a fresh perspective on contract manufacturing, as well as the other latest trends in the market.
Manufacturing technology 1Top
B. Braun Medical Industries is to embrace the digital manufacturing revolution with the installation of new Medical Device Manufacturing Execution System. We explore why systems like this means companies are able to readily scale MES across expanding sites and easily adapt to the future needs of the business. In addition, MES will help companies to capture real-time information and make it available across its sites, as well as connect all its equipment, various information systems and operator interfaces to regulate all aspects of production. We speak to B. Braun about what this means for the industry.
Manufacturing Technology 2Top
New stents and implants for knee replacement surgery is the one of the big stories of the past couple of years. New ultra lightweight and easy to manoeuvre technology is being manufactured that can be produced cost effectively, and reduce the patients’ recovery time. We speak to the chief medical officer EMEA at Johnson and Johnson, Simon Sinclair, about this technology, and the machinery and manufacturing processes needed for innovations like this to happen.
Manufacturing Technology 3 Top
New visualisation devices for internal procedures for a variety of devices are being launched all the time, and many are using new technology that could revolutionise manufacturing procedures especially for quality control. We speak to Boston Scientific about what they’re doing in this area and how they see this sector growing and changing.
Microsensors and flexible electronics in smart lenses offer a closer look at diabetes and glaucoma. In labs around the world, biomedical engineers have been making exciting progress on smart lenses to diagnose diseases and allow unobtrusive and continuous monitoring of patients. In fact, two smart-lens products have already hit the market in Europe to help patients with glaucoma, one of the world’s most common eye diseases. We speak to the team from Verily Life Sciences, Google’s technology offshoot, about what this could mean for manufacturing.
Collaborative robots could help medical device packagers with kitting, assembly, case packing, and palletising. The devices, known as “Cobots” could allow the repeat of certain processes, thus eradicating potential for human error. Some in the industry believe it’s a technology that will further enhance day-to-day operations and add value to the output of workers who engage with cobots. We speak to the British Plastics Federation about what these inventions could mean for the industry.
Biomaterials 1 Top
A new study has paved the way for improved treatments for patients with nerve damage through the use of biomaterials. The technique uses artificial nerve grafts which attempt to improve regeneration and functional recovery in the injured peripheral nervous system, which consists of the nerves outside of the brain and spinal cord. We speak to Professor Abhay Pandit, from the Science Foundation Ireland Centre for Research in Medical Devices, about the research and what it could lead to.
Biomaterials 2 Top
A new product to assist bone formation in spinal fusion surgery developed by DePuy Synthes could change the way some surgeries are conducted. Bone graft substitute comprised of viable, lineage committed bone cells delivers all three properties required for bone formation and is a second generation cellular allograft used to assist in the formation of bone during spinal fusion surgery. We speak to the team who developed this product about how it could help surgeons and lead to new manufacturing breakthroughs.
Could electricity replace opioids in treating chronic pain? An implantable device called a neuromodulator, that essentially tricks the brain into thinking a region of the body is no longer in pain, has made rapid advances in the past few years. We speak to Dr. Allen Burton, Abbott's medical director for neuromodulation, movement disorders and pain, about how manufacturers could take it further.
Electronics 2 Top
Graphene is the latest ‘it’ thing to hit medtech. Medical Device Developments explores how it is being used in wearables, as well as how other new electronics are changing the industry and speak to researchers at Chalmers University in Sweden, who have combined graphene with new electronics into a detector that could lead to new products such as wearable terahertz sensors for medical diagnosis. We speak to Jan Stake, head of the Terahertz and Millimetre Wave Laboratory at Chalmers, about why this is so exciting for the medical device sector.
Electronics 3 Top
Medical device manufacturers think IoT is the solution for medical adherence problems. Vodafone IoT director Erik Brenneis speaks to Medical Device Developments about how IoT could help to overcome this problem by using smart devices, connectivity and the cloud to deliver information about a patient's therapy to healthcare professionals. It claimed that this could save up to $290 billion in "avoidable" spending in the United States alone. What could it mean globally?
Logistics 1 Top
What are the best ways to go about improving customer satisfaction with the use of automation: How has this developed and what is the future outlook? Hans Willems, VP Supply Chain Europe , Boston Scientific speaks to Medical Device Developments about how to automate customer order processing in the most time and resource efficient way, what are the available smart ordering tools and what are the best ones to use and how to increase service levels and customer satisfaction by process standardisation.
Sterilisation 1 Top
Contract sterilisation services for medical devices are an interesting area as appropriate sterilisation packaging in the healthcare sector is a challenging task of the healthcare product manufacturers including medical devices. We look at innovative sterilisation technologies, which are being developed and proposed for use in the manufacture
Materials 1 Top
3D printing in the military is really taking off, but it’s not all 3D printed drones and weaponry: the technology is also serving an important rehabilitative purpose for soldiers who are injured and lose limbs on the battlefield with medical devices. Peter Liacouras, the director of services, at Walter Reed National Military Medical Center’s 3D Medical Applications Center (3DMAC) speaks to Medical Device Developments about new plastics and design that they are using, and how this could move forward into device manufacturing.
Materials 2 Top
3D printed custom implants used for robotic surgery to for bone cancer patients are a new medtech frontier. A combination of 3D printing, robotic surgery and advanced manufacturing are being used by RMIT University in Australia in conjunction with medtech giant Stryker to create tailored implants for patients with bone cancer. While patients are having their cancer removed in the operating theatre, in the next room, a custom implant will be printed to precisely fill the space left after removal of the diseased bone. We speak to Stryker’s director, Research and Development for Asia-Pacific, Rob Wood, who explains how 3D printing is opening new doors for manufacturing in healthcare.
Coatings and surfaces 1 Top
A new coating offers slow-release antiseptic for medical devices. Many medical devices are subject to colonisation by bacteria and in some instances, the body’s immune system can effectively eradicate these microbes, with few or no symptoms for the individual. But for others, however, the microbes multiply and spread, resulting in infection. In some cases, the bacteria can form a biofilm which is much more difficult for the body, or for medicines, to attack. But now, materials have been developed to deliver the antiseptic chlorhexidine over a sustained, controlled period and ease the risk of this. We speak to chief scientific officer of Pertinax Pharma, Dr Michele Barbour, about the how this will work in medical devices.
Using microfluidics to make life easier for diabetic patients is one step closer with new insulin measuring devices coming down the pipeline. We speak to Joel Goldsmith, Abbott senior director of digital platforms, who is working on new technology to further bring these improvements to patients, and the manufacturing processes that this involves.
Microfluidics 2 Top
A new consortium to accelerate the discovery of novel drugs to treat kidney diseases has been formed; The NEPLEX (nephron on a chip with cellular and extracellular matrix complexity) consortium, comprising leading academic institutions including the Universities of Bristol and Cambridge, and Evotec AG, will combine key technologies to develop and build a novel drug discovery device. We speak to Professor Moin Saleem and his group from the University of Bristol, who will contribute human kidney cell lines focusing on the resorption unit about what this could mean for the manufacture of new breakthroughs.
Motors and motion control 1Top
The brushless DC motor market has become increasingly commercially important in recent years following the rising use of electronic systems in novel application streams such as the automotive sector and now it’s moving into medical devices. Whilst, brushless DC motors are more expensive than conventional brushed DC motors, but provide significant benefits in terms of operational efficiency and maintenance requirements, because they offer a higher power-to-volume ratio. We explore what they offer medical device manufacturers.
Lasers and photonics 1Top
Pulsed laser diodes can hasten clinical use of photoacoustic imaging. Recent advances can reduce the size and cost of devices to simplify workflows and increase accessibility. We speak to Manojit Pramanik from Nanyang Technological University, Singapore, who led the research into this about the technology.
The UK Medicines & Healthcare Products Regulatory Agency (MHRA) has released new guidance on human factors for medical devices. The publication was made in reference to the three directives that currently regulate EU medical devices and includes a transition period of three years for the EU Medical Devices Regulations (MDR) and a five year period for the In Vitro Diagnostics Devices Regulations (IVDR). We explore what it means for manufacturers.
The FDA has released a plethora of information and guidance on 3D printing. The agency is the first in the world to provide a comprehensive technical framework advising manufacturers creating medical products on 3D printers. The guides centre especially on the responsibilities of the device maker and what they need to adhere to and communicate to the user. We speak to the Medical Device Manufacturers Association about what they recommend for OEMs and how to stay abreast of changing laws.
Testing and complianceTop
The issue of technology in medical devices moving too fast for regulators to keep up means that medtech companies and manufacturers need their own robust compliance rules to make sure they are adhering to safety levels. We speak to several lawyers specialising in medtech, who give the lowdown on what OEMs need to think about when operating. From faulty equipment, to customer service, working across the Atlantic, or through the EU, Medical Device Developments explores modern compliance woes.
Filtration and fluid controlTop
Pumps, valves and the continuing developments in fluid control for manufacturing systems are an oft overlooked area of the process. We explore the latest advances and trends to keep labs, factories and other facilities ticking over and Kate Scott, a researcher with the MIT Libraries Conservation Lab, and specialises in purification systems in industrial settings and discusses new developments in the industry.